高压氧辅助治疗脑动脉硬化症的疗效

[摘要]评价高压氧(hyperbaricoxygen,HBO)治疗脑动脉硬化症的疗效。例脑动脉硬化症患者随机分为HBO治疗组例,对照组例。通过对两组的症状、体征、血液流变学、治疗前后的改变进行疗效评价,并根据HBO治疗前后脑动脉脉动指数,脑动脉血流的改善,并对HBO治疗脑动脉硬化症的作用机制进行了探讨。HBO组患者眩晕、头痛、失眠、记忆力、计算力、精神状态等的改善较对照组疗效明显(P0.),治疗组血液流变学指标提示全血粘度及血浆粘度均明显降低(P0.01),TCD见HBO治疗后大脑前、中动脉的脉动指数明显下降(P0.05,P0.01);而对照组血液流变学、TCD改善均不明显。HBO治疗脑动脉硬化疗效确切、可靠,优于单纯药物治疗。

[关键词]脑动脉硬化/治疗;高压氧

[作者简介]黄文英(-),女,湖南资兴人,主治医师,主要从事神经内科的临床工作。

TheEffectsofHyperbaricOxygen(HBO)TherapyonPatientswithCerebralArtcriosclerosis

HUANGWen-ying,LIUZhi-zhong,HEYu-zhen,etal(TheFirstPeoplesHospitalofChenzhouCity,Hunan)

[Abstract]Toevaluatetheeffectsofhyperbaricoxygen(HBO)therapyonpatientswithcere-bralarteriosclerosis.SevenHundredcasesofcerebralarteriosclerosiswererandomlydividedintotreamtentgroup(n=,receivinghyperbaricoxygentherapyplusroutinetreatment)andcontrolgroup(n=,onlyreceivingroutinetreatment).TheexaminationsofTCDandbloodrheologyatdifferenperiodswereperformed.Inthetreatmentgroup,therecoveryrateandeffectiverateweresignificantlyhigherthaninthecontrolgroup(P0.01).Inthetreatementgroup,theparameters(wholebloodviscosityandplasmaviscosity)forbloodrheologywereobviouslydecreased(P0.01).TCDrevealedthatthecerebralis-chemiclociwereimprovedinvaryingdegrees.Hyperbaricoxygenplusroutinetreatmentcaneffec-tivelytreatcerebralarteriosclerosis.

[Keywords]cerebralarteriosclerosis/TH;hyperbaricoxygenation

[中图分类号]R.1

[文献标识码]A

[文章编号]-(5)06--03

在我国高压氧于20世纪60年代应用于临床,逐渐被广大学者所重视,其在脑部疾病治疗中的作用得到普遍的